Latest From Our Blog

More evidence resveratrol may fight Alzheimer’s

More evidence resveratrol may fight Alzheimer’s

Resveratrol may help strengthen the blood brain barrier to defend against molecules that cause inflammation, recent research says.

By Shara Rutberg, New Hope Network

Resveratrol, a compound found in red wine, dark chocolate and blackberries, appears to boost the brain’s defense against Alzheimer’s, according to new information gleaned from a 2015 study and published in the journal Neurology. Georgetown University researchers presented the findings at the Alzheimer’s Association International Conference 2016 in July.

“These findings suggest that resveratrol imposes a kind of crowd control at the border of the brain. The agent seems to shut out unwanted immune molecules that can exacerbate brain inflammation and kill neurons,” neurologist Charbel Moussa, MD, PhD, scientific and clinical research director of the Georgetown University Medical Center Translational Neurotherapeutics Program said in a university release. “These are very exciting findings because it shows that resveratrol engages the brain in a measurable way, and that the immune response to Alzheimer’s disease comes, in part, from outside the brain.”

The inflammation that damages the brains of people with Alzheimer’s is believed to be a reaction of the buildup of abnormal proteins that harm neurons. Researchers have believed that the inflammation that worsens the disease came from immune cells that were already in the brain. But this study suggests that some of the immune molecules that can cause inflammation in the blood can enter the brain through a leaky blood-brain barrier. It’s this barrier that resveratrol may help strengthen.

“These new findings are exciting because they increase our understanding of how resveratrol may be clinically beneficial to individuals with Alzheimer’s disease. In particular, they point to the important role of inflammation in the disease, and the potent anti-inflammatory effects of resveratrol,” study leader R. Scott Turner, MD, PhD, director of GUMC’s Memory Disorders Program and co-director of the Translational Neurotherapeutics Program, said in the release.

While resveratrol warrants further testing, it’s not likely to be a solo treatment for Alzheimer’s, said the researchers. It doesn’t defend the brain against tau, a protein aggregate involved in the disease, so a successful treatment would likely combine resveratrol with an agent that targets that protein.

PDF24    Send article as PDF   

A.J. Ali

A.J. Ali, "The Wellness Motivator!" is an award-winning writer, producer, actor, host, voice over artist, emcee and creative visionary. He is the Founder and Executive Producer of EclipseVSC since 1999. A.J. is currently producing and hosting the multimedia wellness entity "Wellness 101" with a vision of helping to change the focus of healthcare in America from sickness to wellness (www.wellness101life.com). To launch the Wellness 101 brand, A.J. did the impossible. Starting with only $500, he traveled through all 50 states in 101 days June 16 through September 24, 2014 -- starting in Melbourne Beach, FL and ending up on a sun soaked beach in Hawaii after changing lives in all 50 states. His "True Champion's 30-Day Challenge" book is transforming lives nationwide (www.TrueChampions30DayChallenge.com). Now, Wellness 101 is taking human transformation to another level through holistic wellness. A.J. has more than 30 years experience in sports and entertainment as an athlete, artist and social entrepreneur. He has founded and owned two pro soccer teams and has spearheaded hundreds of successful projects. A.J. created and starred in the TV show "Good Fellas of Baltimore" on Fox in 2011, which raised more than $250,000 for charities in Baltimore and inspired fans to join the cast to help people in need. As an on-air talent and voice over artist, his enthusiastic love of people makes him believable and inspirational. As a wellness speaker and emcee, he is inspiring. An accomplished writer with a conversational style, his work is transformative. His 2007 song "Through the Darkness, Into the Light," compilation music CD "Survivor Celebration" and Survivor Celebration campaign helping cancer survivors won the coveted Hollywood FAME Award for National Community Service. As a philanthropist and entrepreneur, A.J. has raised more than $25 million for charities. He teaches his charity event success methods through a workshop called "MAKE IT RAIN." He is proud to be a U.S. Air Force Veteran (83-87). His mantra is "LOVE is the answer." He is an avid golfer.

No Comments

Leave a Comment